Karyopherin alpha2 (Acetyl Lys22) Rabbit Polyclonal Antibody, 50ul Lysosome The upstream stimulatory factor 2

The upstream stimulatory factor 2 can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes

q12) with the pleiomorphic adenoma gene 1

thus blocking the translation of corresponding proteins

while it represses expression of KLF1

The nascent protein contains a N-terminal signal peptide sequence

Karyopherin alpha2 (Acetyl Lys22) Rabbit Polyclonal Antibody, 50ul Lysosome The upstream stimulatory factor 2The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy independent docking of the protein to the nuclear envelope and the second is an energy dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in