KDM5B Polyclonal Antibody, 50ul DNA Oligo Synthesis In cardiac myocytes

In cardiac myocytes

This gene consists of two exons and encodes a 104aa protein

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Demethylates both di- and trimethylated H3 'Lys-9' residue

Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway

KDM5B Polyclonal Antibody, 50ul DNA Oligo Synthesis In cardiac myocytesThis gene encodes a lysine specific histone demethylase that belongs to the jumonji ARID domain containing family of histone demethylases. The encoded protein is capable of demethylating tri , di and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair.