SMAD7 Polyclonal Antibody, 50ul Peptide Library and murine studies suggest a

and murine studies suggest a role in tumor-associated tissue remodeling

the transiently superficial layer that envelopes the developing epidermis

this gene encodes a protein that is not closely related to other known growth factors

Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues

AMPK is an important energy-sensing enzyme that monitors cellular energy status

SMAD7 Polyclonal Antibody, 50ul Peptide Library and murine studies suggest aThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding