Sodium Channel inhibitor 1 henicol inhibits the activation of nuclear

inhibits the activation of nuclear factor-κB

10-100 fold more potent in cell-based enzyme occupancy assays than against cathepsin B

Smiles: NC1N=C(N)N=C2N=C(C(=NC=12)C1=CC(O)=CC=C1)C1=CC(O)=CC=C1

5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide

Formula: C19H21N5O2

Sodium Channel inhibitor 1 henicol inhibits the activation of nuclearSodium Channel inhibitor1, one of 3 Oxoisoindoline 1 carboxamides, is a novel and selective voltage gated sodium channel for pain treatment. IC50 Value: 0. 16 uM ( Na v1. 7, V hold 90mV); 0. 41 uM (Na v1. 7, V hold 90mV) Target: Na v1. 7Sodium Channel inhibitor1 demonstrated concentration dependent efficacy in preclinical behavioral pain models. Product information CAS Number: 1198117 23 5 Molecular Weight: 473. 42 Formula: C24H19F4N3O3 Chemical Name: