PRT4165 - E3 Ubiquitin-ligase Bmi1/Ring1A Inhibitor. CAS# 31083-55-3 30002 InChi: InChI=1S/C29H32N6O4S

InChi: InChI=1S/C29H32N6O4S

Chemical Name: (3E

It has been shown to improve the reprogramming efficiency of mouse embryonic fibroblasts (MEFs) into induced pluripotent stem (iPS) cells

RN-1 can abolish long-term memory formation without affecting short-term memory in the novel object recognition (NOR) mouse model

and restored mean corpuscular volume and mean cell hemoglobin of red bloods cells

PRT4165 - E3 Ubiquitin-ligase Bmi1/Ring1A Inhibitor. CAS# 31083-55-3 30002 InChi: InChI=1S/C29H32N6O4SPRT4165, CAS No. 31083 55 3, is a small molecule inhibitor of polycomb repressive complex 1, which inhibits ubiquitin signaling at DNA double strand breaks. PRT4165 is a potent inhibitor of PRC1 mediated H2A ubiquitylation in vivo and in vitro. The drug also inhibits the accumulation of all detectable ubiquitin at sites of DNA double strand breaks (DSBs), the retention of several DNA damage response proteins in foci that form around DSBs, and the