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Nutlin-3, (4R5S, and 4S5R) Catalog No.:M7686-10 3)28)22-18(26)11-15(12-19(22)27)8-9-21(31)32/h4-9

SKU: 97504128228

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Nutlin-3, (4R5S, and 4S5R) Catalog No.:M7686-10 3)28)22-18(26)11-15(12-19(22)27)8-9-21(31)32/h4-9Nutlin 3 is an inhibitor of MDM2 (human homolog of murine double minute 2), which disrupts its interaction with p53, leading to the stabilization and activation of p53. Nutlin 3 activates the p53 pathway and efficiently induces apoptosis in tumours with amplified MDM2 gene and overexpression of MDM2 protein. Product information CAS Number: 548472 68 0 Molecular Weight: 581. 49 Formula: C30H30Cl2N4O4 Synonym: () Nutlin 3 Nutlin 3 Related CAS Number:

Store: gaabil.dk · Domain: gaabil.dk

Description

3)28)22-18(26)11-15(12-19(22)27)8-9-21(31)32/h4-9

Formula: C25H24N4O2

Molecular Weight: 816

In vitro cytotoxicity and in vivo efficacy

InChiKey: FUXFIVRTGHOMSO-UHFFFAOYSA-N

Nutlin-3, (4R5S, and 4S5R) Catalog No.:M7686-10 3)28)22-18(26)11-15(12-19(22)27)8-9-21(31)32/h4-9Nutlin 3 is an inhibitor of MDM2 (human homolog of murine double minute 2), which disrupts its interaction with p53, leading to the stabilization and activation of p53. Nutlin 3 activates the p53 pathway and efficiently induces apoptosis in tumours with amplified MDM2 gene and overexpression of MDM2 protein. Product information CAS Number: 548472 68 0 Molecular Weight: 581. 49 Formula: C30H30Cl2N4O4 Synonym: () Nutlin 3 Nutlin 3 Related CAS Number:

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