L-165041 Size:Solid 10 mg It shows more than 100-fold

It shows more than 100-fold selectivity for mTOR relative to PI3Kα

200-fold) and atypical isoforms (>10000-fold)

SW044248 is a non-canonical Top1 inhibitor

PROTAC FKBP Degrader-3 is a potent FKBP degrader

53)41(52)56-7

L-165041 Size:Solid 10 mg It shows more than 100-foldL 165041, also known as L 165,041, is a potent and selective agonist of the nuclear receptor PPAR (Ki = 9 nM, EC50 = ~500 nM for hPPAR ). L 165041 promotes VEGF mRNA stabilization in HPV18 harboring HeLa cells through a receptor independent mechanism. L 165041 inhibits VEGF induced angiogenesis, but the antiangiogenic effect is not related to PPAR. L 165041 inhibits rat vascular smooth muscle cell proliferation and migration via inhibition of cell