(-)-Huperzine A 060 JTP-74057) or 10 mg/kg of

JTP-74057) or 10 mg/kg of HWA486

compound list : BAY-87-2243

Entinostat (MS-275) was used at 1 µM final concentration in vitro and in cellular assays

It is a unctionalized cereblon ligand for PROTAC research and development

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

(-)-Huperzine A 060 JTP-74057) or 10 mg/kg of( ) Huperzine A (Huperzine A) is an alkaloid isolated from a Chinese club moss, with neuroprotective activity. ( ) Huperzine A is a potent, highly specific, reversible and blood brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. ( ) Huperzine A also is non competitive antagonist of N methyl D aspartate glutamate (NMDA) receptor. ( ) Huperzine A is developed for the research of neurodegenerative diseases, including