IPA-3 Size:10mg solid release an amount of LDH

release an amount of LDH (12

InChi: InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7

which also tested as a positive control

CAS Number: 686772-17-8

InChiKey: ZQVLPYMRXLPMDX-KEAIDYLOSA-N

IPA-3 Size:10mg solid release an amount of LDHIPA 3 is a potent and selective PAK1 inhibitor. IPA 3 inhibits the growth of liver cancer cells by suppressing PAK1 and NF B activation. IPA 3 treatment significantly inhibited the growth of HCC cells. The mechanisms through which IPA 3 treatment suppresses HCC cell growth are enhancement of apoptosis and blockage of activation of NF B. IPA 3 not only inhibits the HCC cell growth, but also suppresses the metastatic potential of HCC cells. Nude mouse