Bestatin Hydrochloride loride dihydrate) InChi: InChI=1S/2C10H14N2

InChi: InChI=1S/2C10H14N2

RG108 can potentially be used to maintain embryonic stem (ES) cells in an undifferentiated state as well as replace transcription factors in both mouse and human cell reprogramming

Barzilai-Tutsch H

whereas inhibits total SAPK/JNK activity with an IC50 of 3–10 μM

(2007) Mol

Bestatin Hydrochloride loride dihydrate) InChi: InChI=1S/2C10H14N2Ubenimex, also known as NK 421 and Bestatin, is a CD13 inhibitor. Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism. Ubenimex synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer