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Topotecan Hydrochloride Catalog No.:M9750-2 Effect of KAD-1229

Topotecan Hydrochloride Catalog No.:M9750-2 Effect of KAD-1229

Name: Topotecan Hydrochloride Catalog No.:M9750-2 Effect of KAD-1229
Brand: gaabil.dk
SKU: 84674310548
Price: 75.00 USD
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SKU: 84674310548

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Topotecan Hydrochloride Catalog No.:M9750-2 Effect of KAD-1229Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I DNA covalent complexes, inhibiting religation of topoisomerase I mediated single strand DNA breaks and producing potentially lethal double strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline based alkaloid

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Description

Effect of KAD-1229

Chemical Name: tert-butyl 6-(5-oxo-4-(1H-1

Formula: C16H12O4

(2012) Mol Cancer Ther

37 and 61% TGI

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