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Zosuquidar trihydrochloride - CAS# 167465-36-3 Size:Solid 2 mg ARRY-520 had low nanomolar antiproliferative

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Zosuquidar trihydrochloride - CAS# 167465-36-3 Size:Solid 2 mg ARRY-520 had low nanomolar antiproliferativeZosuquidar, also known as LY 335979, is a potent P glycoprotein (P gp) inhibitor, which binds with high affinity to P glycoprotein and inhibits P glycoprotein mediated multidrug resistance (MDR). P glycoprotein, encoded by the MDR 1 gene, is a member of the ATP binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product derived cytotoxic agents. Product information CAS Number: 167465

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Description

ARRY-520 had low nanomolar antiproliferative activity in tumor cell lines and specifically inhibits KSP (kinesin-5 or Eg5)

116644-53-2 (free base)

6-dichloro-4-(3

Calamita G

InChi: InChI=1S/C31H29Cl2F2N3O4/c1-30(2

Zosuquidar trihydrochloride - CAS# 167465-36-3 Size:Solid 2 mg ARRY-520 had low nanomolar antiproliferativeZosuquidar, also known as LY 335979, is a potent P glycoprotein (P gp) inhibitor, which binds with high affinity to P glycoprotein and inhibits P glycoprotein mediated multidrug resistance (MDR). P glycoprotein, encoded by the MDR 1 gene, is a member of the ATP binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product derived cytotoxic agents. Product information CAS Number: 167465

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