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SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 InChi: InChI=1S/C23H19NO3/c1-26-17-11-7-15(8-12-17)21(16-9-13-18(27-2)14-10-16)22-19-5-3-4-6-20(19)24-23(22)25/h3-14H

SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 InChi: InChI=1S/C23H19NO3/c1-26-17-11-7-15(8-12-17)21(16-9-13-18(27-2)14-10-16)22-19-5-3-4-6-20(19)24-23(22)25/h3-14H

Name: SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 InChi: InChI=1S/C23H19NO3/c1-26-17-11-7-15(8-12-17)21(16-9-13-18(27-2)14-10-16)22-19-5-3-4-6-20(19)24-23(22)25/h3-14H
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SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 InChi: InChI=1S/C23H19NO3/c1-26-17-11-7-15(8-12-17)21(16-9-13-18(27-2)14-10-16)22-19-5-3-4-6-20(19)24-23(22)25/h3-14HSC 79, CAS No. 305834 79 1, is an activator of Akt that blocks its membrane translocation while allowing its phosphorylation, in the cytosol, by upstream kinases. SC 79 is a potential treatment for alcohol induced osteonecrosis of the femoral head. SC 79 injections inhibited alcohol induced osteonecrosis. Alcohol induced ONFH is associated with suppression of p Akt Ser473 in the Akt GSK3 catenin signaling pathway in bone mesenchymal stem cells.

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InChi: InChI=1S/C23H19NO3/c1-26-17-11-7-15(8-12-17)21(16-9-13-18(27-2)14-10-16)22-19-5-3-4-6-20(19)24-23(22)25/h3-14H

PubMed PMID: 26331795

209783-80-2

Major Depressive Disorder and Kappa Opioid Receptor Antagonists

53(2):289-96

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