ZM-447439 Catalog No.:M7710-2 (2015) J Med Chem

(2015) J Med Chem

InChi: InChI=1S/C27H34F3N7O3/c1-35-10-8-16(9-11-35)32-24(38)18-12-22(40-3)20(13-19(18)28)33-26-31-14-21-23(34-26)37(17-6-4-5-7-17)15-27(29

ML-109 contains an aminal

and 25 mg/kg prolongs median survival to 19

cells remain viable 1 week post-treatment even at 10 μM of Nutlin-3

ZM-447439 Catalog No.:M7710-2 (2015) J Med ChemZM447439 is a potent and selective inhibitor of aurora A and B kinase with putative anti tumoral activity. ZM induced apoptosis in a concentration and time dependent manner. Product information CAS Number: 331771 20 1 Molecular Weight: 513. 59 Formula: C29H31N5O4 Synonym: ZM447439 ZM 447439 Chemical Name: N (4 ((6 methoxy 7 (3 morpholinopropoxy)quinazolin 4 yl)amino)phenyl)benzamide Smiles: