KB-R7943 - CAS# 182004-65-5 Catalog No.:M6421-2 In addition to NCXrev

In addition to NCXrev

PubMed Central PMCID: PMC4871611

DASA-58 inhibits LPS-induced Hif-1α and IL-1β

Smiles: CC(C)C1=CC(=NC(N)=N1)C1=CC=C(F)C2=CC=CC=C21

InChi: InChI=1S/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22

KB-R7943 - CAS# 182004-65-5 Catalog No.:M6421-2 In addition to NCXrevKB R7943, CAS No. 182004 65 5, is a potent, selective inhibitor of the reverse mode of the Na+ Ca2+ exchanger (IC50 = 0. 7 M). KB R7943 does not modify secondary pathology in the thalamus following focal cerebral stroke in rats. KB R7943 blocks opening of the mitochondrial permeability transition pore. KB R7943 restores endothelium dependent relaxation induced by advanced glycosylation end products in rat aorta. KB R7943 inhibits high glucose induced