Loxoprofen I-3 discussion 21

discussion 21

H-1152 effects on intraocular pressure and trabecular meshwork morphology of rat eyes

and is selective for the type A endothelin receptor (ETA)

SB505124 (10 µM) impairs Smad2 phosphorylation and CTGF and α-SMA expression in vitro

2ClH/c11-9(12)17-15-5-7-2-1-3-8(4-7)6-16-18-10(13)14

Loxoprofen I-3 discussion 21Loxoprofen is a non steroidal anti inflammatory drug in the propionic acid derivatives group. loxoprofen is a non selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. Product information CAS Number: 68767 14 6 Molecular Weight: 246. 30 Formula: C15H18O3 Chemical Name: 2 {4 [(2 oxocyclopentyl)methyl]phenyl}propanoic acid Smiles: CC(C(O)=O)C1C=CC(CC2CCCC2=O)=CC=1 InChiKey: YMBXTVYHTMGZDW