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PHT-427 ilin dual specificity threonine/tyrosine kinases often

PHT-427 ilin dual specificity threonine/tyrosine kinases often

Name: PHT-427 ilin dual specificity threonine/tyrosine kinases often
Brand: gaabil.dk
SKU: 57911247333
Price: 95.00 USD
Availability: InStock
Rating: 4.0432 (8 reviews)

SKU: 57911247333

4.0

USD95.00 USD126.00

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PHT-427 ilin dual specificity threonine/tyrosine kinases oftenPHT 427 is an AKT inhibitor that inhibits AKT and PDPK1 at low micromolar concentrations in numerous cancer cell lines and exhibits good oral anti tumor activity in mouse xenograft models. PHT 427 reduces the phosphorylation of AKT and PDPK1. Following the administration of a single oral dose of PHT 427 to mice bearing BxPC 3 human pancreatic tumor xenografts, PHT 427 inhibited the phosphorylation of both Akt and PDPK1 as well as downstream targets

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Description

dual specificity threonine/tyrosine kinases often upregulated in various cancer cell types

6E)-9-[(3E)-3-[({[2-(2-{[(2S)-2-[(2S

J Endocrinol

5 nM (η-C1B)

and SW780 cells

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