BCX 4430 3022 59(1):289-98

59(1):289-98

IWP-4 also causes a significant down regulation of SPARC and COL1A1

RS-127445 is found to have nM affinity and 1000 fold selectivity for the 5-HT2B receptor

CHR-2797 is converted into a pharmacologically active acid product (CHR-79888) inside cells

Epetraborole was in development for the treatment of infections caused by multidrug-resistant Gram-negative pathogens

BCX 4430 3022 59(1):289-98Galidesivir, also known as BCX4430 and Immucillin A, is an antiviral drug and an adenosine analog. Galidesivir was originally intended as a treatment for Hepatitis C, but subsequently developed as a potential treatment for deadly filovirus infections such as Ebola virus disease and Marburg virus disease. Galidesivir also shows broad spectrum antiviral effectiveness against a range of other RNA virus families, including bunyaviruses, arenaviruses,