AY 254 Catalog No.:M7571-10 Targeting stromal-induced pyruvate kinase M2

Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread

Smiles: CC1SC(=CC=1[C@@H]1NCCC2=CC=C(Cl)C=C21)C(=O)C1=CN=CN=C1N[C@@H]1C[C@H](COS(N)(=O)=O)[C@@H](O)C1

Chemical Name: 2-Aminoethyl (R)-2

Toxicol Appl Pharmacol

Talukdar S

AY 254 Catalog No.:M7571-10 Targeting stromal-induced pyruvate kinase M2Potent PAR2 biased agonist. Selectively activates ERK1 2 signaling (EC50 = 2 nM for ERK1 2 phosphorylation versus 80 nM for Ca2+ release). Reduces cytokine induced caspase 3 8 activation, promotes scratch wound healing, and induces IL 8 secretion, in human colorectal cancer (HT29) cells in vitro. Product information CAS Number: 2093408 03 6 Molecular Weight: 631. 77 Formula: C30H49N9O6 Synonym: AY254 AY 254 Chemical Name: N ((6S,9S,12S,15S) 1 amino 6