TAK-779 Catalog No.:M10030-2 9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide

9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide

11aS)-1-hydroxy-11a-methyl-1H

Amifostine is a phosphorothioate proposed as a radiation-protective agent

851881-60-2

Pharmacokinetics and pharmacodynamics of PF-05231023

TAK-779 Catalog No.:M10030-2 9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamideTAK 779 is a C C chemokine receptor type 5 (CCR5) receptor antagonist potentially for the treatment of HIV infection. Treatment with TAK 779 reduced incidence and severity of experimental autoimmune encephalomyelitis. It strongly inhibited migration of CXCR3 CCR5 bearing CD4+, CD8+ and CD11b+ leukocytes to the CNS. TAK 779 did not reduce proliferation of anti myelin oligodendrocyte glycoprotein T cells, the production of IFN gamma by T cells or CXCR3