BAY-57-1293 - CAS# 348086-71-5 Catalog No.:M6482-10 ADX47273 increased extracellular signal-regulated kinase

ADX47273 increased extracellular signal-regulated kinase and cAMP-responsive element-binding protein phosphorylation in hippocampus and prefrontal cortex

Chemical Name: (S)-2-(4-chlorophenyl)-1-(4-((5R

Inhibition of MEK5 by BIX-02188 induces apoptosis in cells expressing the oncogenic mutant FLT3-ITD

Smiles: CC1=CC(=CC(C)=C1)[C@@H]1CCCN1CC1C=CC(=CC=1)OC1=CC=C(C=C1F)C(N)=O

selective and orally bioavailable HDAC/LSD1 dual Inhibitor

BAY-57-1293 - CAS# 348086-71-5 Catalog No.:M6482-10 ADX47273 increased extracellular signal-regulated kinaseBAY 57 1293, CAS No. 348086 71 5, is a potent helicase primase inhibitor. BAY 57 1293 inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the viral primase helicase complex. In various rodent models of HSV infection the antiviral activity of BAY 57 1293 in vivo was found to be superior compared to all compounds currently used to treat HSV infections. The compound