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LY2109761 - TGFβ Inhibitor. CAS# 700874-71-1 size:Contact sales@xcessbio.com for quotation 2014 Feb 10

LY2109761 - TGFβ Inhibitor. CAS# 700874-71-1 size:Contact [email protected] for quotation 2014 Feb 10

Name: LY2109761 - TGFβ Inhibitor. CAS# 700874-71-1 size:Contact sales@xcessbio.com for quotation 2014 Feb 10
Brand: gaabil.dk
SKU: 35563961699
Price: 68.00 USD
Availability: InStock
Rating: 4.1926 (19 reviews)

SKU: 35563961699

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LY2109761 - TGFβ Inhibitor. CAS# 700874-71-1 size:Contact [email protected] for quotation 2014 Feb 10LY2109761, CAS No. 700874 71 1, is a highly potent and selective TGF receptor type I and type II (TRI II) inhibitor with Ki of 38 nM and 300 nM respectively. Blocking TRI II kinase activity with LY2109761 completely suppresses both the basal and TGF 1 stimulated migration and invasion of L3. 6pl GLT cells, and completely suppresses TGF induced Smad2 phosphorylation. LY2109761 treatment at 1 nM is sufficient to significantly block the migration and

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Description

2014 Feb 10

oral administration

Cote-Sierra J

Pedranzini L

CXCL1 concentration in the serum peaking at 3 h after the injection

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