Cathepsin S inhibitor amectin 4-dihydroxyoxane-2-carboxylic acid

4-dihydroxyoxane-2-carboxylic acid

Pirfenidone potently inhibits the production of the proinflammatory cytokines

also known as RG7388 and RO5503781

4-oxadiazol-5-yl)piperidin-1-yl)methanone

InChiKey: HCZKYJDFEPMADG-UHFFFAOYSA-N

Cathepsin S inhibitor amectin 4-dihydroxyoxane-2-carboxylic acidLY3000328 is a Cathepsin S inhibitor with excellent in vitro potency and selectivity against other cysteine proteases. LY3000328 is currently in clinical trials. Cathepsin S (Cat S) plays an important role in many pathological conditions, including abdominal aortic aneurysm (AAA). Inhibition of Cat S may provide a new treatment for AAA. Product information CAS Number: 1373215 15 6 Molecular Weight: 484. 52 Formula: C25H29FN4O5 Chemical Name: (3R,4S) 4