RG3039 0081 and proteasome-dependent manner in HCT116

and proteasome-dependent manner in HCT116 cells and Mino cells

Smiles: C[C@]12CC[C@H](O)CC1=CC[C@@H]1[C@@H]2CC2[C@H]1CC[C@]1(O[C@@H]3C[C@H](C)CN[C@H]3[C@H]1C)C=2C

Stensbøl TB

Formula: C27H26ClN3O7S2

CAS Number: 1234356-69-4

RG3039 0081 and proteasome-dependent manner in HCT116RG3039 (PF 06687859, PF 6687859, Quinazoline 495) is an orally bioavailable and brain penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4. 2 nM and IC90 of 40 nM, respectively. Product information CAS Number: 1005504 62 0 Molecular Weight: 432. 35 Formula: C21H23Cl2N5O Synonym: PF 06687859 Chemical Name: 5 ((1 (2,6 dichlorobenzyl)piperidin 4 yl)methoxy)quinazoline 2,4 diamine Smiles: