Vinflunine Size:Solid 2 mg Efficacy and safety of once-daily

Efficacy and safety of once-daily GW870086 a novel selective glucocorticoid in mild-moderate asthmatics: a randomised

JNJ63533054

Molecular Weight: 582

PubMed Central PMCID: PMC3968083

PubMed PMID: 25726556

Vinflunine Size:Solid 2 mg Efficacy and safety of once-dailyVinflunine is a bi fluorinated derivative of the semi synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities. Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine, vinblastine and vinorelbine; this effect on microtubule dynamics results in cell cycle arrest in mitosis and apoptosis.