Palbociclib isethionate Size:Solid 10 mg A dual CCR2/CCR5 chemokine antagonist

A dual CCR2/CCR5 chemokine antagonist

PMID: 31826639

Daun02 may be useful as a prodrug-activating enzyme in suicide gene therapy and has the potential to increase the selective toxicity of conventional antitumor agents

Sagittatoside-A

55837-20-2

Palbociclib isethionate Size:Solid 10 mg A dual CCR2/CCR5 chemokine antagonistPalbociclib, also known as PD 0332991, is an orally available cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib selectively inhibits cyclin dependent kinase 4 (CDK4) and 6 (CDK6), thereby inhibiting retinoblastoma (Rb) protein phosphorylation early in the G1 phase leading to cell cycle arrest. This suppresses DNA replication and decreases tumor cell proliferation. CDK4 and 6 are serine threonine kinases that