H-1152 Size:Solid 2 mg or treating Hh pathway dependent

or treating Hh pathway dependent cancer in vitro and in vivo

and has slight activity against HDAC8 (IC50 ~0

J Endocrinol

PubMed PMID: 22806357

is a selective and potent calcium ion-sensing receptor (CaSR) antagonist

H-1152 Size:Solid 2 mg or treating Hh pathway dependentH 1152 is a selective inhibitor of ROCK. H 1152 effects on intraocular pressure and trabecular meshwork morphology of rat eyes. H 1152 is a more specific, stronger and membrane permeable inhibitor of Rho kinase with a Ki value of 1. 6 nM, but poor inhibitor of other serine threonine kinases. Product information CAS Number: 451462 58 1 Molecular Weight: 319. 42 Formula: C16H21N3O2S Synonym: H 1152 H1152 Chemical Name: 4 methyl 5 {[(2S) 2 methyl 1,4