SB-269970 Hydrochloride - CAS# 261901-57-9 oprenaline Hydrochloride In the mouse xenograft models

In the mouse xenograft models using subcutaneously transplanted UM-UC-14 and MGHU3

4]triazin-7-yl)cyclohexanecarboxylic acid

0 nM against MDA-MB-231 cell line

Risperidone mesylate(R 64 766 mesylate) is a serotonin 5-HT2 receptor blocker

compared to the Cat S inhibitor LHVS (IC50=0

SB-269970 Hydrochloride - CAS# 261901-57-9 oprenaline Hydrochloride In the mouse xenograft modelsSB269970 HCl is a potent 5 HT7A antagonist (pKi = 8. 9) that demonstrates >50 fold binding selectivity over 5 HT5A and >250 fold selectivity over 5 HT1, 5 HT2, 5 HT4, 5 HT6, adrenergic 1, dopamine D2, and dopamine D3 receptors. It is also reported to block adrenergic 2 receptors in guinea pig vas deferens. SB 269970 has been used to target the 5 HT7 receptor in the study of schizophrenia like cognitive deficits. Product information CAS Number: 261901