Lost Cities Variant:with 6th Expedition Points are earned both from

Points are earned both from placing trains and completing tickets but uncompleted tickets lose you points

that card must be numbered exactly one higher or lower than the card on top of the discard pile

players must choose one of their faction's two powers

The Mutation challenge adds a fifth (purple) disease that behaves differently than the original four

players race to slap the pile — creating a "slamwich"

Lost Cities Variant:with 6th Expedition Points are earned both fromLost Cities is a card game in the Kosmos two player series. The game originally consisted of a single deck of cards of rank 210 in five different colors with three special "handshakes" in each suit, but as of 2019 the game now includes six colored suits, with the sixth color being optional for gameplay. A game board is included to organize discarded cards and help players organize their card collections.