Losartan D4 3835 PubMed Central PMCID: PMC4866744
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Losartan D4 3835 PubMed Central PMCID: PMC4866744Losartan D4 (DuP 753 D4) is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. Product information CAS Number: 1030937 27 9 Molecular Weight: 426. 94 Formula: C22H23ClN6O Synonym: DuP 753 D4 Cozaar D4 Chemical Name: (2 butyl 4 chloro 1 {[2' (2H 1,2,3,4 tetrazol 5 yl)(2,3,5,6 H) [1,1' biphenyl] 4 yl]methyl} 1H imidazol 5 yl)methanol Smiles:
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