Savolitinib Catalog No.:M8740-10 PC-9VanR (EGFRExon 19 deletion/T790M)

PC-9VanR (EGFRExon 19 deletion/T790M)

The effects of Erlotinib HCl in combination with gemcitabine are considered additive in KRAS-mutated pancreatic cancer cells

Eflornithine for the treatment of human African trypanosomiasis

5H-thieno[3

It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM)

Savolitinib Catalog No.:M8740-10 PC-9VanR (EGFRExon 19 deletion/T790M)Savolitinib, also known as Volitinib, AZD6094 or HMPL 504, is an orally bioavailable inhibitor of the c Met receptor tyrosine kinase with potential antineoplastic activity. Volitinib selectively binds to and inhibits the activation of c Met in an ATP competitive manner, and disrupts c Met signal transduction pathways. This may result in cell growth inhibition in tumors that overexpress the c Met protein. Product information CAS Number: 1313725 88 0