TGR5 Polyclonal Antibody, 100ul Centrifugal Filter The encoded protein binds specific

The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking

This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain

is capable of binding specifically to methylated DNA

which is a motif known to be involved in protein-protein interactions

and contributes to the regulation of immune responses

TGR5 Polyclonal Antibody, 100ul Centrifugal Filter The encoded protein binds specificGPBAR1 encodes a member of the G protein coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.