DARPP-32 Polyclonal Antibody, 50ul Electronic Pipette Mutations in this gene are

Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies

FLRTs may function in cell adhesion and/or receptor signalling

As a result

Polymorphisms in this protein appear to be tissue specific and influence protease targeting

PFDN1 (prefoldin subunit 1) encodes a member of the prefoldin beta subunit family

DARPP-32 Polyclonal Antibody, 50ul Electronic Pipette Mutations in this gene arePPP1R1B encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, PPP1R1B may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for PPP1R1B.