PSB10 Rabbit Polyclonal Antibody, 50ul DNA Fragments Mutations in this gene are

Mutations in this gene are associated with sensory/motor neuropathy with ataxia

ATP-sensitive inward rectifier potassium channel 11

and contains one protein kinase domain

A cis-acting segment found in the 5' UTR is involved in stress-dependent induction| resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions

The protein encoded by this gene is a ubiquitously expressed nuclear protein

PSB10 Rabbit Polyclonal Antibody, 50ul DNA Fragments Mutations in this gene areThe proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP ubiquitin dependent process in a non lysosomal pathway. An essential function