NUD10 Rabbit Polyclonal Antibody, 100ul Digital Burette Alternative splicing of this gene

Alternative splicing of this gene generates two transcript variants diverging in the 3' region

but the full-length nature of only two transcript variants has been determined

Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation

Mutations in this gene have been associated with KBG syndrome| which is characterized by macrodontia| distinctive craniofacial features| short stature| skeletal anomalies| global developmental delay| seizures and intellectual disability

Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery

NUD10 Rabbit Polyclonal Antibody, 100ul Digital Burette Alternative splicing of this geneThis gene is a member of the nudix (nucleoside diphosphate linked moiety X) type motif containing family. The encoded protein is a phosphohydrolase and may regulate the turnover of diphosphoinositol polyphosphates. The turnover of these high energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to the regulation of