CSPP1 Polyclonal Antibody, 50ul Cell Function Analysis COPS2 is an essential component

COPS2 is an essential component of the COP9 signalosome complex (CSN)

The protein encoded by this gene localizes to perinuclear endosomes

|Contains 1 acyl carrier domain

It bears similarity to a zinc finger protein which acts as a transcriptional activator

The protein encoded by CDC5L (cell division cycle 5 like) shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product

CSPP1 Polyclonal Antibody, 50ul Cell Function Analysis COPS2 is an essential componentThis gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.