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CNGB3 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This gene encodes a protein

SKU: 98102084065

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CNGB3 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This gene encodes a proteinThis gene encodes the beta subunit of a cyclic nucleotide gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.

Store: gaabil.dk · Domain: gaabil.dk

Description

This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain

Additional isoforms| resulting from the use of alternate downstream translation initiation sites| have also been noted

display vasoconstrictor and chemotactic activities

ETS transcription factor is activated by signal-induced phosphorylation

CMTM3 belongs to the chemokine-like factor gene superfamily

CNGB3 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This gene encodes a proteinThis gene encodes the beta subunit of a cyclic nucleotide gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.

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