HMGN1/2/3/4 Rabbit Polyclonal Antibody, 50ul Recombinant Protein NBPF1 is a member of

NBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

promotes extension of ssDNA and partial ssDNA (pssDNA) substrates (PubMed: 18503084

thymus and certain germ cell tumors

Aberrant expression of the gene is associated with cancer proliferation in numerous tissues

and specifically binds to intronic polypyrimidine tracts

HMGN1/2/3/4 Rabbit Polyclonal Antibody, 50ul Recombinant Protein NBPF1 is a member ofThe protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein HMG17 the encoded protein may help maintain an open chromatin configuration around transcribable genes.