MARCH2 Polyclonal Antibody, 100ul Recombinant Protein Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include transporter activity and transmembrane transporter activity

Inhibin beta C chain is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes

This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome

Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

RHOA encodes a member of the Rho family of small GTPases

MARCH2 Polyclonal Antibody, 100ul Recombinant Protein Gene Ontology (GO) annotations relatedMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.