PYGM Rabbit Polyclonal Antibody, 20ul Antibody Humanization an N-terminal DNA-binding domain| a

an N-terminal DNA-binding domain| a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression

and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis

The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and

The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues

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PYGM Rabbit Polyclonal Antibody, 20ul Antibody Humanization an N-terminal DNA-binding domain| aThis gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency) a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants.