Vav(Phospho Tyr160) Polyclonal Antibody, 20ul Site-directed Mutagenesis The N-terminal region of the

The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity

May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT

SPC and SPD

Alternatively spliced transcript variant encoding distinct isoforms have been observed

either expressed from similar genes or the result of alternative splicing

Vav(Phospho Tyr160) Polyclonal Antibody, 20ul Site-directed Mutagenesis The N-terminal region of theThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.