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VPREB Polyclonal Antibody, 20ul Palm Micro Centrifuges It is a potent activator

SKU: 96676052135

4.6
PLN97.20 PLN138.20

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VPREB Polyclonal Antibody, 20ul Palm Micro Centrifuges It is a potent activatorThe protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig mu chain to form a molecular complex which is expressed on the surface of pre B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B cell differentiation.

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Description

It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli

The preB cell receptor is found on the surface of proB and preB cells

which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production

Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis

amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection

VPREB Polyclonal Antibody, 20ul Palm Micro Centrifuges It is a potent activatorThe protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig mu chain to form a molecular complex which is expressed on the surface of pre B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B cell differentiation.

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