LAX1 Polyclonal Antibody, 100ul Biochemical Reagents Several alternatively spliced transcripts have

Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins

suitable for most glass and plastic culture medium storage bottles

but our experiment always detected a 60-70kDa protein by western blot

and a conserved C-terminal SH2 domain

This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB

LAX1 Polyclonal Antibody, 100ul Biochemical Reagents Several alternatively spliced transcripts haveNegatively regulates TCR (T cell antigen receptor) mediated signaling in T cells and BCR (B cell antigen receptor) mediated signaling in B cells.,induction: Up regulated in T cells following TCR engagement.,PTM: Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit: When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity: Expressed in