IRS-1 Polyclonal Antibody, 50ul[BT-AP04649] Protein Modification This gene encodes a protein

This gene encodes a protein that contains the GAP-related domain (GRD)| a characteristic domain of GTPase-activating proteins (GAPs)

In human cardiac tissue| this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation

It may be involved in cellular excitability of restricted neurons in the central nervous system

This proto-oncogene| highly-expressed in a variety of tumor cell lines| belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes

It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion

IRS-1 Polyclonal Antibody, 50ul[BT-AP04649] Protein Modification This gene encodes a proteinIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.