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LFTY2 Rabbit Polyclonal Antibody, 50ul Electronic Pipette Mutations in this gene are

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LFTY2 Rabbit Polyclonal Antibody, 50ul Electronic Pipette Mutations in this gene areThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein which plays a role in left right asymmetry determination of organ systems during development. The

Store: gaabil.dk · Domain: gaabil.dk

Description

Mutations in this gene are associated with Joubert syndrome-22

UNG encodes one of several uracil-DNA glycosylases

and exon 6 encodes the cytoplasmic tail

It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity

NUB1 encodes a protein that functions as a negative regulator of NEDD8

LFTY2 Rabbit Polyclonal Antibody, 50ul Electronic Pipette Mutations in this gene areThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein which plays a role in left right asymmetry determination of organ systems during development. The

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