MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix consisting of KRTHB1

consisting of KRTHB1

This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails

Mutations in this gene are a cause of colorectal cancer (CRC)

Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster

It contains a Sec7 domain

MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix consisting of KRTHB1Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007