Zic1/2/3/4/5 Polyclonal Antibody, 50ul Cell Senescence subunit:Interacts with actin monomer

subunit:Interacts with actin monomer

This protein binds to an extended groove that is formed by the interaction of CBF1

and the kinase activity of the complex is regulated throughout the cell cycle mainly by fluctuating levels of Dbf4

which is an upstream activator of both p38 and JNK MAPKs

this gene participates in viral defense regulation as a negative regulator of interferon-beta

Zic1/2/3/4/5 Polyclonal Antibody, 50ul Cell Senescence subunit:Interacts with actin monomerZIC1 (Zic family member 1) encodes a member of the ZIC family of C2H2 type zinc finger proteins. Members of this family are important during development. Aberrant expression of ZIC1 is seen in medulloblastoma, a childhood brain tumor. ZIC1 is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. ZIC1 encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.