TIAM1 Polyclonal Antibody, 100ul DNA Oligo Synthesis Some patients with Ehlers-Danlos syndrome

Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity

Isoform 4 is expressed in lung and pancreas (at protein level)

a non-TATA-box basal promoter element common to these 2 types of genes

and altered sleep patterns

The encoded protein is highly similar to the mouse and rat CK1 delta homologs

TIAM1 Polyclonal Antibody, 100ul DNA Oligo Synthesis Some patients with Ehlers-Danlos syndromeModulates the activity of RHO like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP dissociation stimulator protein that stimulates the GDP GTP exchange activity of RHO like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.,Belongs to the TIAM family.,Contains 1 DH (DBL homology) domain.,Contains 1 PDZ (DHR) domain.,Contains 1 PH domain.,Contains 1 RBD (Ras binding) domain.,Contains 2