HA-tag Polyclonal Antibody, 50uL[BT-AP09803] Reagent Reservoirs Defects in RB1 are a

Defects in RB1 are a cause of childhood cancer retinoblastoma (RB)

The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family

Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta

This gene is implicated in B cell development and lymphomagenesis

The role of receptor is supported by the presence of 27 CUB domains

HA-tag Polyclonal Antibody, 50uL[BT-AP09803] Reagent Reservoirs Defects in RB1 are aThe HA tag (Y P Y D V P D Y A) is derived from an epitope (amino acids 98 106) of the influenza hemagglutinin (HA) protein. HA tag is used as a general epitope tag in expression vectors for many recombinant proteins. The presence of HA tag facilitates the detection, isolation and purification of recombinant fusion proteins.