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UNC5D Polyclonal Antibody, 20ul Yeast Expression This gene is involved in

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UNC5D Polyclonal Antibody, 20ul Yeast Expression This gene is involved inReceptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.,PTM: Phosphorylated on cytoplasmic tyrosine residues.,PTM:

Store: gaabil.dk · Domain: gaabil.dk

Description

This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene

Role in cell fate determination

Mutations in HGF are associated with nonsyndromic hearing loss

Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy

and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors

UNC5D Polyclonal Antibody, 20ul Yeast Expression This gene is involved inReceptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.,PTM: Phosphorylated on cytoplasmic tyrosine residues.,PTM:

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